APPLICATION OF RESISTANCE TRAINING IN MENTAL HEALTH DISORDERS, LATEST DISCOVERIES
Abstract
Mental disorders such as depression and anxiety are leading causes of disability. This review evaluates the potential of resistance training as an adjunctive therapy and its effect on symptoms. A synthesis of meta-analyses, systematic reviews, and randomized controlled trials indicates neurobiological benefits (enhanced brain plasticity and increased BDNF), hormonal effects (reduced cortisol), and anti-inflammatory effects (decreased TNF-α and IL-6). Resistance training also improves self-esteem, sleep quality, and social connectedness, increasing its applicability across patient populations. As a complement to pharmacotherapy and psychotherapy, it offers additional benefits and fewer barriers to implementation. Its program flexibility allows easy integration into personalized care and public-health strategies. Future research should standardize protocols, optimize intensity and duration, and assess long-term effects. Technologies — wearables and mobile apps — may improve adherence and accessibility. Resistance training has the potential to substantially enrich mental healthcare and improve quality of life for people with depression, anxiety, and other mental disorders.
References
Evans-Lacko S, Aguilar-Gaxiola S, Al-Hamzawi A, Alonso J, Benjet C, Bruffaerts R, et al. Socio-economic variations in the mental health treatment gap for people with anxiety, mood, and substance use disorders: results from the WHO World Mental Health (WMH) surveys. Psychol Med. 2017/11/27 wyd. 2018;48:1560–71.
Barahona-Fuentes G, Huerta Ojeda Á, Chirosa-Rios L. Effects of training with different modes of strength intervention on psychosocial disorders in adolescents: A systematic review and meta-analysis. Int J Environ Res Public Health. 2021;18:9477.
Gordon BR, McDowell CP, Lyons M, Herring MP. The effects of resistance exercise training on anxiety: a meta-analysis and meta-regression analysis of randomized controlled trials. Sports Med. 2017;47:2521–32.
Augustin N, Bendau A, Heuer S, Kaminski J, Ströhle A. Resistance training in depression. Dtsch Ärztebl Int. 2023;120:757.
Noetel M, Sanders T, Gallardo-Gómez D, Taylor P, del Pozo Cruz B, Van Den Hoek D, et al. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials. bmj. 2024;384.
Carter T, Morres ID, Meade O, Callaghan P. The effect of exercise on depressive symptoms in adolescents: a systematic review and meta-analysis. J Am Acad Child Adolesc Psychiatry. 2016;55:580–90.
De Vries YA, De Jonge P, van den Heuvel E, Turner EH, Roest AM. Influence of baseline severity on antidepressant efficacy for anxiety disorders: meta-analysis and meta-regression. Br J Psychiatry. 2016;208:515–21.
White RL, Vella S, Biddle S, Sutcliffe J, Guagliano JM, Uddin R, et al. Physical activity and mental health: a systematic review and best-evidence synthesis of mediation and moderation studies. Int J Behav Nutr Phys Act. 2024;21:134.
Li A, Sun Y, Li M, Wang D, Ma X. Effects of elastic band resistance training on the physical and mental health of elderly individuals: A mixed methods systematic review. Plos One. 2024;19:e0303372.
Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br. J. Sports Med. 2020. s. 1451–62.
Abou Sawan S, Nunes EA, Lim C, McKendry J, Phillips SM. The health benefits of resistance exercise: beyond hypertrophy and big weights. Exerc Sport Mov. 2023;1:e00001.
Syed-Abdul MM. Benefits of resistance training in older adults. Curr Aging Sci. 2021;14:5–9.
Marinelli R, Parker AG, Levinger I, Bourke M, Patten R, Woessner MN. Resistance training and combined resistance and aerobic training as a treatment of depression and anxiety symptoms in young people: A systematic review and meta‐analysis. Early Interv Psychiatry. 2024;
Donyaei A, Kiani E, Bahrololoum H, Moser O. Effect of combined aerobic–resistance training and subsequent detraining on brain‐derived neurotrophic factor (BDNF) and depression in women with type 2 diabetes mellitus: A randomized controlled trial. Diabet Med. 2024;41:e15188.
Schuch FB, Vancampfort D, Richards J, Rosenbaum S, Ward PB, Stubbs B. Exercise as a treatment for depression: a meta-analysis adjusting for publication bias. J Psychiatr Res. 2016;77:42–51.
Kim S-W, Park H-Y, Jung W-S, Lim K. Effects of Twenty-Four Weeks of Resistance Exercise Training on Body Composition, Bone Mineral Density, Functional Fitness and Isokinetic Muscle Strength in Obese Older Women: A Randomized Controlled Trial. Int J Environ Res Public Health. 2022;19:14554.
Silva JKT, Menêses AL, Parmenter BJ, Ritti-Dias RM, Farah BQ. Effects of resistance training on endothelial function: a systematic review and meta-analysis. Atherosclerosis. 2021;333:91–9.
Lopes JSS, Machado AF, Micheletti JK, de Almeida AC, Cavina AP, Pastre CM. Effects of training with elastic resistance versus conventional resistance on muscular strength: A systematic review and meta-analysis. SAGE Open Med. 2019;7:2050312119831116.
Moraes HS, Silveira HS, Oliveira NA, Matta Mello Portugal E, Araújo NB, Vasques PE, et al. Is strength training as effective as aerobic training for depression in older adults? A randomized controlled trial. Neuropsychobiology. 2020;79:141–9.
Partridge L, Deelen J, Slagboom PE. Facing up to the global challenges of ageing. Nature. 2018;561:45–56.
Radjevic N, Ponorac N. Effects of the eight-week resistance training program using stable and unstable surfaces to arms and shoulders’ muscular strength parameters with untrained individuals. J Phys Educ Sport. 2018;18:1756–60.
Carneiro L, Afonso J, Ramirez-Campillo R, Murawska-Ciałowciz E, Marques A, Clemente FM. The effects of exclusively resistance training-based supervised programs in people with depression: a systematic review and meta-analysis of randomized controlled trials. Int J Environ Res Public Health. 2020;17:6715.
Roca P, Vazquez C, Diez G, Brito-Pons G, McNally RJ. Not all types of meditation are the same: Mediators of change in mindfulness and compassion meditation interventions. J Affect Disord. 2021;283:354–62.
Chiang L-Y, Tsai J-M, Chen C-H, Tsai L-Y. Effects of Elastic Band Resistance Exercise on Physiological Indicators, Depression and Quality of Life of the Elderly in Nursing Homes. Int J Gerontol. 2024;18.
Sanchez-Lastra MA, Varela S, Cancela JM, Ayán C. Upper versus lower body resistance exercise with elastic bands: effects on cognitive and physical function of institutionalized older adults. Eur Geriatr Med. 2022;13:907–16.
Pavlova I, Vynogradskyi B, Kurchaba T, Zikrach D. Influence of leisure-time physical activity on quality of life of Ukrainian students. J Phys Educ Sport. 2017;17:1037–42.
Meng R, Yu C, Liu N, He M, Lv J, Guo Y, et al. Association of depression with all-cause and cardiovascular disease mortality among adults in China. JAMA Netw Open. 2020;3:e1921043–e1921043.
Takeshima N, Islam MM, Rogers ME, Rogers NL, Sengoku N, Koizumi D, et al. Effects of nordic walking compared to conventional walking and band-based resistance exercise on fitness in older adults. J Sports Sci Med. 2013;12:422.
Serra-Prat M, Lorenzo I, Palomera E, Ramírez S, Yébenes JC. Total body water and intracellular water relationships with muscle strength, frailty and functional performance in an elderly population. A cross-sectional study. J Nutr Health Aging. 2019;23:96–101.
Pilu A, Sorba M, Hardoy MC, Floris AL, Mannu F, Seruis ML, et al. Efficacy of physical activity in the adjunctive treatment of major depressive disorders: preliminary results. Clin Pract Epidemiol Ment Health. 2007;3:1–4.
Roma MFB, Busse AL, Betoni RA, Melo AC de, Kong J, Santarem JM, et al. Effects of resistance training and aerobic exercise in elderly people concerning physical fitness and ability: a prospective clinical trial. Einstein Sao Paulo. 2013;11:153–7.
Lederman O, Suetani S, Stanton R, Chapman J, Korman N, Rosenbaum S, et al. Embedding exercise interventions as routine mental health care: implementation strategies in residential, inpatient and community settings. Australas Psychiatry. 2017;25:451–5.
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