THE IMPACT OF REGULAR PHYSICAL ACTIVITY ON REDUCING EXACERBATION FREQUENCY, ENHANCING DISEASE CONTROL, AND IMPROVING QUALITY OF LIFE IN PATIENTS WITH BRONCHIAL ASTHMA

Keywords: Asthma, Exercise-Induced Asthma, Physical Activity, Bronchoconstriction, Asthma Exacerbations

Abstract

Introduction: Bronchial asthma is a chronic inflammatory airway disease with variable obstruction and hyperresponsiveness. Symptoms such as wheezing, dyspnea, chest tightness, and coughing fluctuate over time. Globally, asthma affects over 235 million people and represents a major health and economic burden. While physical exertion was once discouraged due to exercise-induced bronchoconstriction (EIB), current guidelines, including GINA, recommend regular physical activity as part of management.

Objective: To evaluate whether physical activity benefits asthma patients of varying severity by improving control, reducing exacerbations, and enhancing quality of life.

Methods: A narrative literature review was performed using PubMed. Inclusion criteria: English-language full texts from 2013–2025, limited to reviews and RCTs. Eighteen relevant articles were analyzed.

Results: Exercise improves asthma control (e.g., 23% ACQ improvement in REACT) and quality of life (AQLQ). It reduces exacerbations and reliever use (53% vs. 20% exacerbation-free in one study). Aerobic training enhances FEV1 and FVC, while Inspiratory Muscle Training increases PImax. No consistent effect on airway inflammation was observed. Recommended modalities include aerobic, resistance, and flexibility training individualized via the FITT principle. Aquatic exercise may lower EIB risk due to humid air. EIB is managed by warm-up routines, pre-exercise SABAs, ICS for control, and optional ICS-LABA or LTRA. Benefits are pronounced in obese and moderate/severe asthma, especially with weight loss. Monitoring air quality and symptoms during activity is essential.

Conclusion: Regular physical activity is safe, cost-effective, and improves asthma outcomes when tailored and combined with appropriate EIB management.

References

Allen, H., Price, O. J., Hull, J. H., & Backhouse, S. H. (2022). Asthma medication in athletes: A qualitative investigation of adherence, avoidance and misuse in competitive sport. Journal of Asthma, 59(4), 811–822. https://doi.org/10.1080/02770903.2021.1881968

Dickinson, J. W. (2024). Breathing pattern changes in response to bronchoconstriction in physically active adults. Journal of Asthma. Advance online publication. https://doi.org/10.1080/02770903.2024.0000000

Grande, A. J., Silva, V., Andriolo, B. N., Riera, R., Parra, S. A., & Peccin, M. S. (2014). Water-based exercise for adults with asthma. Cochrane Database of Systematic Reviews, 2014(7), CD010456. https://doi.org/10.1002/14651858.CD010456.pub2

Hansen, E. S. H., Pitzner-Fabricius, A., Toennesen, L. L., Rasmusen, H. K., Hostrup, M., Hellsten, Y., Backer, V., & Henriksen, M. (2020). Effect of aerobic exercise training on asthma in adults: A systematic review and meta-analysis. European Respiratory Journal, 56, 2000146. https://doi.org/10.1183/13993003.00146-2020

Jaakkola, J. J. K., Jaakkola, M. S., & Koponen, A. (2019). Regular exercise improves asthma control: The Regular Exercise and Asthma Control Trial (REACT). Scientific Reports, 9, 13745. https://doi.org/10.1038/s41598-019-50368-6

Kocak, C., Pehlivan, E., & Baslilar, S. (2025). High- vs. low-intensity inspiratory muscle training in asthma: Effects on respiratory muscles, exercise performance, dyspnea, and health-related quality of life. Journal of Asthma. Advance online publication. https://doi.org/10.1080/02770903.2025.2519103

Kuder, M. M., Clark, M., Cooley, C., Prieto-Centurion, V., Danley, A., Riley, I., Siddiqi, A., Weller, K., Kitsiou, S., & Nyenhuis, S. M. (2021). A systematic review of the effect of physical activity on asthma outcomes. Journal of Allergy and Clinical Immunology: In Practice, 9(9), 3407–3421.e8. https://doi.org/10.1016/j.jaip.2021.04.048

Kuo, Y.-C., Lin, Y.-H., & Hsu, T.-Y. (2021). 12-Week inspiratory muscle training and breathing exercises improve physical activity and clinical symptoms in patients with asthma. International Journal of Environmental Research and Public Health, 18(6), 3267. https://doi.org/10.3390/ijerph18063267

LaForce, C., Chipps, B. E., Albers, F. C., Reilly, L., Johnsson, E., Andrews, H., et al. (2022). Albuterol/budesonide for the treatment of exercise-induced bronchoconstriction in patients with asthma: The TYREE study. Annals of Allergy, Asthma & Immunology, 128(2), 169–177. https://doi.org/10.1016/j.anai.2021.10.020

Lista-Paz, A., Bouza Cousillas, L., Jácome, C., Fregonezi, G., Labata-Lezaun, N., Llurda-Almuzara, L., & Pérez-Bellmunt, A. (2023). Effect of respiratory muscle training in asthma: A systematic review and meta-analysis. Annals of Physical and Rehabilitation Medicine, 66(3), 101691. https://doi.org/10.1016/j.rehab.2022.101691

Liu, W., Feng, Z., Song, S., Lei, S., & Guo, W. (2025). The effectiveness of physical activity in asthma. Clinical Respiratory Journal, 19(4), e70075. https://doi.org/10.1111/crj.70075

McLoughlin, R. F., Clark, V. L., Urroz, P. D., Gibson, P. G., & McDonald, V. M. (2022). Increasing physical activity in severe asthma: A systematic review and meta-analysis. European Respiratory Journal, 60(6), 2200546. https://doi.org/10.1183/13993003.00546-2022

Moraes, L., Silva, D., Viana, D., Vianna, L., & Vasconcelos, A. (2013). Physical activity and asthma: A systematic review and meta-analysis of observational studies. PLoS ONE, 8(11), e79112. https://doi.org/10.1371/journal.pone.0079112

Ora, J., De Marco, P., Gabriele, M., Cazzola, M., & Rogliani, P. (2024). Exercise-induced asthma: Managing respiratory issues in athletes. Journal of Functional Morphology and Kinesiology, 9(1), 15. https://doi.org/10.3390/jfmk9010015

Price, O. J., Papadopoulos, N. G., Amérigo, D. A., Backer, V., Bougault, V., Del Giacco, S., Gawlik, R., Eguiluz-Gracia, I., Heffler, E., Janson, C., McDonald, V. M., Moreira, A., Simpson, A., & Bonini, M. (2025). Exercise recommendations and practical considerations for asthma management: An EAACI position paper. Allergy, 80(6), 1572–1591. https://doi.org/10.1111/all.16573

Ricketts, H. C., Buchan, D. S., Steffensen, F., Chaudhuri, R., Baker, J. S., & Cowan, D. C. (2022). Physical activity levels in asthma: Relationship with disease severity, body mass index and novel accelerometer-derived metrics. Journal of Asthma, 60(4), 824–834. https://doi.org/10.1080/02770903.2022.2031235

Rodriguez Bauza, D. E., & Silveyra, P. (2021). Asthma, atopy, and exercise: Sex differences in exercise-induced bronchoconstriction. Experimental Biology and Medicine, 246(12), 1400–1409. https://doi.org/10.1177/15353702211003858

Valkenborghs, N., McDonald, V. M., Gardiner, P. A., & Gibson, P. G. (2024). Effects of moderate- and vigorous-intensity aerobic exercise training on asthma outcomes: A randomized controlled trial. Journal of Allergy and Clinical Immunology: In Practice, 12(10), 2744–2753. https://doi.org/10.1016/j.jaip.2024.06.015

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Published
2025-09-23
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Kamil Kerknawi, Paulina Mikulec, Michalina Zagalska, Marta Turek, Angelika Kędzierska, Natalia Nafalska, Krzysztof Feret, Małgorzata Stopyra, & Aleksandra Ćwirko-Godycka. (2025). THE IMPACT OF REGULAR PHYSICAL ACTIVITY ON REDUCING EXACERBATION FREQUENCY, ENHANCING DISEASE CONTROL, AND IMPROVING QUALITY OF LIFE IN PATIENTS WITH BRONCHIAL ASTHMA. International Journal of Innovative Technologies in Social Science, 3(3(47). https://doi.org/10.31435/ijitss.3(47).2025.3974