VIRAL WARTS IN ATHLETES: A COMMON DERMATOLOGICAL CHALLENGE WITH EVOLVING DIAGNOSTIC AND THERAPEUTIC APPROACHES
Abstract
Aim of the Study: This review aims to analyze the prevalence, risk factors, diagnostic strategies and treatment modalities of viral warts in athletes, a population predisposed to cutaneous HPV infections. The paper focuses on dermoscopic features, therapeutic approaches, and return-to-play recommendations, aiming to provide clinicians with practical guidance for managing HPV-related skin lesions in physically active individuals.
Study methods: A narrative review was conducted based on a selection of 22 peer-reviewed articles obtained from PubMed and Scopus, including randomized controlled trials, clinical guidelines, dermoscopic case series, and epidemiological studies. Additional reference materials included dermatological textbooks and online resources for healthcare professionals. Emphasis was placed on athlete-specific data, non-invasive diagnostic methods and evidence-based management strategies.
Results: Athletes are especially vulnerable to HPV due to frequent skin trauma, occlusion, moisture exposure, and shared environments. Verruca vulgaris, verruca plantaris, and verruca plana are the most common manifestations. Dermoscopy improves diagnostic accuracy by identifying patterns such as red or black dots, papilliform projections, and disrupted skin lines. Treatments vary by wart type and severity; while cryotherapy and salicylic acid remain first-line, newer therapies such as immunomodulators and photodynamic therapy show promising outcomes. Preventive measures, such as protective gloves and lesion coverage, are critical to control transmission in athletic settings.
Conclusions: Cutaneous warts significantly impact athletes’ health, performance, and participation. Effective management relies on early diagnosis, targeted treatment, and education on preventive practices. A multidisciplinary approach involving dermatologists, sports physicians, and trainers is essential to reduce transmission risk and ensure safe return to sport.
References
Wilson, E. K., Deweber, K., Berry, J. W., & Wilckens, J. H. (2013). Cutaneous infections in wrestlers. Sports Health, 5(5), 423–437. https://doi.org/10.1177/1941738113481179
Zhu, P., Qi, R. Q., Yang, Y., et al. (2022). Clinical guideline for the diagnosis and treatment of cutaneous warts (2022). Journal of Evidence-Based Medicine, 15(3), 284–301. https://doi.org/10.1111/jebm.12494
Wieland, U., & Kreuter, A. (2020). Human papillomavirus-associated skin diseases. In G. Plewig, W. H. C. Burgdorf, T. Ruzicka, et al. (Eds.), Braun-Falco’s dermatology (4th ed., pp. 1217–1232). Springer.
Papadopoulou, S., et al. (2021). Skin infections in beach volleyball athletes: A focus on viral etiologies. Viruses, 13(11), 2107. https://doi.org/10.3390/v13112107
Kim, Y. S., et al. (2018). Skin infections among high school wrestlers: A 5-year epidemiologic study. Sports Health, 10(5), 447–454. https://doi.org/10.1177/1941738118789954
Adams, B. B. (2004). Dermatologic disorders of the athlete. The Physician and Sportsmedicine, 32(7), 33–40. https://doi.org/10.3810/psm.2004.07.444
Lübbe, J., & Rufli, T. (1995). Verrucae vulgares in swimmers and communal shower users. Journal of Adolescent Health, 16(4), 282–285. https://doi.org/10.1016/0735-6757(95)90136-1
Roach, M. C., & Chretien, J. H. (1995). Common hand warts in athletes: Association with trauma to the hand. Journal of American College Health, 44(3), 125–126. https://doi.org/10.1080/07448481.1995.9939105
Jelinek, J., et al. (2023). Prevalence and management of warts in contact sport athletes. Skin Health and Disease, 3(2), e70776. https://doi.org/10.1002/hsr2.70776
Kwiek, B., & Szepietowski, J. C. (2024). The psychosocial burden of cutaneous warts: A large cross-sectional study. Scientific Reports, 14(1), 960. https://doi.org/10.1038/s41598-024-80608-7
Kurpiewska, J., et al. (2024). Treatment patterns and outcomes in patients with recalcitrant warts. Archives of Dermatological Research, 316(3), 259–266. https://doi.org/10.1007/s00403-024-03014-z
Jang, Y. H., et al. (2022). Combination therapy with cryotherapy and immunotherapy in recalcitrant viral warts: A prospective study. Dermatologic Therapy, 35(5), e15935. https://doi.org/10.1111/dth.15935
Dong, H., Shu, D., Campbell, T. M., Frühauf, J., Soyer, P., & Hofmann-Wellenhof, R. (2011). Dermatoscopy of genital warts. Journal of the American Academy of Dermatology, 64(5), 859–864.
Zhang, Y., Jiang, S., Lin, H., Guo, X., & Zou, X. (2018). Application of dermoscopy image analysis technique in diagnosing urethral condylomata acuminata. Anais Brasileiros de Dermatologia, 93(1), 67–71. https://doi.org/10.1590/abd1806-4841.20186527
Bruggink, S. C., et al. (2010). Warts: Spontaneous regression and treatment options. BMJ, 340, c1031. https://doi.org/10.1136/bmj.c1031
Steele, K., et al. (2003). Natural history and treatment of viral warts in children: A prospective cohort study. Archives of Disease in Childhood, 88(3), 236–239. https://doi.org/10.1136/adc.88.3.236
Gheit, T., et al. (2022). Human papillomavirus and skin cancer. Viruses, 16(11), 1782. https://doi.org/10.3390/v16111782
Al-Gurairi, F. T., et al. (2002). Efficacy of topical 5% imiquimod in recalcitrant cutaneous warts. Clinical and Experimental Dermatology, 27(6), 521–524. https://doi.org/10.1046/j.1365-2230.2002.01078.x
Lipke, M. M. (2006). An armamentarium of wart treatments. American Family Physician, 73(5), 863–868.
Sterling, J. C., et al. (2011). Guidelines for the management of cutaneous warts. Drugs, 71(10), 1211–1219. https://doi.org/10.2165/11592190-000000000-00000
Gibbs, S., et al. (2002). Local treatments for cutaneous warts: Systematic review. BMJ, 325(7362), 461. https://doi.org/10.1136/bmj.325.7362.461
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