TUMOR RELATED EPILEPSY - CASE REPORT AND LITERATURE REVIEW AND COMPARISON

Marcelina Kurek; Justyna Małyska; Aleksandra Wiśniewska; Karolina Kasprzak; Małgorzata Kuczek; Stanisław Kasprzak; Sebastian Turek; Aleksandra Franczuk

doi:10.31435/ijitss.3(47).2025.3881

Marcelina Kurek Students’ Scientific Association of Pediatric Neurology, Medical University of Lublin, Lublin, Poland https://orcid.org/0009-0001-4904-0295
Justyna Małyska Students’ Scientific Association of Pediatric Neurology, Medical University of Lublin, Lublin, Poland https://orcid.org/0000-0002-6693-491X
Aleksandra Wiśniewska Students’ Scientific Association of Pediatric Neurology, Medical University of Lublin, Lublin, Poland https://orcid.org/0009-0008-7319-3962
Karolina Kasprzak Students’ Scientific Association of Pediatric Neurology, Medical University of Lublin, Lublin, Poland https://orcid.org/0009-0001-4287-6428
Małgorzata Kuczek Students’ Scientific Association of Pediatric Neurology, Medical University of Lublin, Lublin, Poland https://orcid.org/0009-0004-2936-3857
Stanisław Kasprzak Students’ Scientific Association of Pediatric Neurology, Medical University of Lublin, Lublin, Poland https://orcid.org/0009-0001-1748-0704
Sebastian Turek Students’ Scientific Association of Pediatric Neurology, Medical University of Lublin, Lublin, Poland https://orcid.org/0009-0002-9883-1867
Aleksandra Franczuk Students’ Scientific Association of Pediatric Neurology, Medical University of Lublin, Lublin, Poland https://orcid.org/0009-0000-8043-6194

DOI: https://doi.org/10.31435/ijitss.3(47).2025.3881

Keywords: Child Epilepsy, Tumor Related Epilepsy, Surgical Treatment, Child Nervous Sustem Tumor, Epilepsy Surgical Treatment

Abstract

Tumor-related epilepsy is a recognized entity in pediatric neurology, most often linked to low-grade epilepsy-associated tumors (LEATs). We report the case of a 13-year-old girl presenting with two generalized tonic-clonic seizures, after which MRI revealed a small right occipital/parietal cortical lesion, radiologically suggestive of a low-grade glial tumor, most consistent with ganglioglioma. The patient developed obesity, depressive disorder with suicide attempt, and self-harming behaviors, which complicated her clinical course. Despite antiepileptic therapy, seizure control remained suboptimal due to irregular medication use. Neurosurgical evaluation recommended resection after further imaging with neuronavigation, but surgery was postponed. This case highlights the challenges of managing epilepsy associated with extratemporal LEATs and underscores the importance of a multidisciplinary approach that includes neurology, neurosurgery, psychiatry, and oncology to address both neurological and psychosocial outcomes. The literature case reports comparison highligts the different symptoms, treatment methods and treatment outcomes of treatment of tumor related epilepsy. It is important to perform imagining after seziures occured.

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