REHABILITATION AFTER ACL RECONSTRUCTION AND THE RISK OF SECONDARY CONTRALATERAL INJURY: A LITERATURE REVIEW OF RETURN TO SPORT TIME AND FUNCTIONAL CONTROL
Abstract
Anterior cruciate ligament (ACL) injuries are highly prevalent among athletes participating in pivoting sports and often result in functional limitations and long-term performance decline. While ipsilateral re-ruptures have been extensively studied, the risk of contralateral ACL injuries following reconstruction remains insufficiently explored. This review aimed to analyze literature published between 2020 and 2025 to investigate the relationship between rehabilitation duration and the incidence of contralateral ACL injury, as well as to propose return-to-sport (RTS) recommendations. A narrative review was conducted using PubMed, MDPI, ScienceDirect, and Google Scholar, with 20 studies meeting the inclusion criteria. These studies focused on athletic populations aged 15 to 40 years and addressed RTS timing and secondary injury outcomes. Results showed that athletes who returned to sport before nine months post-surgery had up to a fourfold increased risk of contralateral ACL injury. Key risk factors included lower limb strength asymmetry (LSI <90%), insufficient psychological readiness (ACL-RSI <70), and compensatory biomechanical patterns such as stiffer landings and altered joint loading. The findings support a minimum rehabilitation duration of 9–12 months, with RTS decisions guided by functional, psychological, and biomechanical criteria to reduce the risk of reinjury.
References
Ricupito, R., Grassi, A., Mourad, F., Di Filippo, L., et al. (2025). Anterior Cruciate Ligament Return to Play: “A Framework for Decision Making”. Journal of Clinical Medicine, 14(7), 2146. https://www.mdpi.com/2077-0383/14/7/2146
Gozal, K., & Sadiwidayat, K.S. (2025). Secondary Injury Rates in Patients Following ACL Reconstruction: Systematic Review and Meta-Analysis. International Journal of Medical Reviews. https://www.ijmedrev.com/article_219809.html
Lindskog, J., Högberg, J., Senorski, R.H., et al. (2025). Cruciate Ligament Reconstruction and Second ACL Injury Risk. Journal of Orthopaedic & Related Surgery. https://www.sciencedirect.com/science/article/pii/S0749806325000465
Yamanashi, Y., Mutsuzaki, H., Kawashima, T., et al. (2024). Early ACL Reconstruction and Return to Sports in Youth Athletes. Medicina, 60(8), 1229. https://www.mdpi.com/1648-9144/60/8/1229
Wilczyński, B., Forelli, F., Hewett, T.E. (2024). Functional Deficits in Non-Elite Soccer Players After ACL Reconstruction. Cureus. https://www.cureus.com/articles/325003
Seilern und Aspang, J., et al. (2025). Midterm Outcomes of ACL Reconstruction in Skeletally Immature Athletes. Orthopaedic Journal of Sports Medicine. https://journals.sagepub.com/doi/abs/10.1177/23259671251322758
Dutaillis, B., Collings, T., Bellinger, P. (2025). Lower Limb Strength & Jump Metrics After ACLR. Knee Surgery, Sports Traumatology, Arthroscopy. https://esskajournals.onlinelibrary.wiley.com/doi/abs/10.1002/ksa.12694
Sandon, A., Kvist, J., Hedevik, H. (2025). Return to Competition After ACL Reconstruction in Swedish Football Players. https://esskajournals.onlinelibrary.wiley.com/doi/abs/10.1002/ksa.12579
Warnecke, B.F., Richter, C., King, E. (2024). Biomechanical Asymmetries at 9 Months Post-ACL Reconstruction. OJSM. https://journals.sagepub.com/doi/abs/10.1177/23259671241276826
Bourne, M., Collings, T., Bellinger, P. (2025). Time-Course Changes in Strength and Jump Post-ACLR. BMJ Open Sport & Exercise Medicine. https://bmjopensem.bmj.com/content/11/Suppl_1/A6.1
Zaffagnini, S., Di Paolo, P.A.S., Viotto, M. (2025). Return to Sport After ACL Injury. Springer. https://link.springer.com/content/pdf/10.1007/978-3-031-58351-3_449.pdf
Arner, J.W., Bradley, J.P. (2024). Practice Patterns and RTS Timing in NFL Physicians for ACLR. OJSM. https://journals.sagepub.com/doi/abs/10.1177/23259671241274139
Nyland, J., Richards, J.A., Wera, J. (2025). Post-ACL Rehabilitation Focused on Contralateral Injury Prevention. Springer. https://link.springer.com/content/pdf/10.1007/978-3-031-58351-3_448.pdf
Powers, K., Moen, R., Siarkas, G. (2024). Cyclops Lesion and Contralateral Injury in Lacrosse Player. Clinical Practice in Athletic Training. https://scholars.indianastate.edu/clinat/vol7/iss3/13/
Wood, A., Hargreaves, M., Manfredi, J.N. (2025). RTS Testing and Contralateral ACL Tears. AJSM. https://journals.sagepub.com/doi/abs/10.1177/03635465241313194
Fältström, A., Forssblad, M. (2025). Young Age and Contralateral Injury Risk in Footballers. KSSTA. https://esskajournals.onlinelibrary.wiley.com/doi/abs/10.1002/ksa.12580
McAleese, T., Welch, N., King, E. (2025). Factors Associated with Contralateral ACL at 5-Year Follow-Up. AJSM. https://journals.sagepub.com/doi/abs/10.1177/03635465241313386
Brinkman, J.C., Tummala, S.V. (2025). Outcomes After Multiply Revised ACL Reconstruction in Athletes. OJSM. https://journals.sagepub.com/doi/pdf/10.1177/23259671251337478
Ihab, E. (2025). Effect of AposTherapy on Lower Limb Biomechanics in ACL Athletes. FIMS Dubai. http://64.226.120.165/handle/123456789/2039
Zago, J., Santos, E.G., Silva, H.S. (2024). Kinesiophobia and Contralateral ACL Injury Risk. MTP Rehabilitation Journal. https://www.mtprehabjournal.com/revista/article/view/1377
Views:
16
Downloads:
3
Copyright (c) 2025 Maciej Sobczyk, Weronika Stachera, Julia Stępień, Barbara Wołoszyn, Patrycja Rzeźnik, Julia Guzowska, Aleksandra Chajnowska, Aleksandra Borowy, Wiktoria Suchcicka, Małgorzata Zach

This work is licensed under a Creative Commons Attribution 4.0 International License.
All articles are published in open-access and licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). Hence, authors retain copyright to the content of the articles.
CC BY 4.0 License allows content to be copied, adapted, displayed, distributed, re-published or otherwise re-used for any purpose including for adaptation and commercial use provided the content is attributed.