НАРУШЕНИЯ В МИКРОЭЛЕМЕНТНОМ СОСТАВЕ ВОЛОС У ДЕТЕЙ С РАЗЛИЧНОЙ СТЕПЕНЬЮ ТЯЖЕСТИ КРАПИВНИЦЫ

Abstract

One of the urgent problems of Pediatrics is a high incidence of allergic, especially in young children. Difficulties in the treatment of patients with allergic dermatoses are often associated with an incomplete understanding of the mechanism of the disease, which is necessary for the development of pathogenic treatment. The most studied mechanisms are now immune reactions underlying allergic inflammation in the background trouble regulatory processes of the nervous system, as well as frequent changes in the gastrointestinal tract. These modern experimental and clinical studies have shown that the change in the composition of minerals in the body can influence during immunological processes, including in the development of allergic reactions. The aim of the study was to investigate the characteristics of microelement status in children with urticaria. The study of microelement status in the hair samples was carried out by X-ray fluorescence analysis. The hair has been chosen as test biological substrates due to the ability to accumulate over time trace of growth and hence reflection integral information about the contents of macro- and microelements in the body for the last 2-3 months. The study involved 40 patients with varying degrees of disease severity. It was found that all children with a mild form of hives dismikroelementoz characterized by absolute reduction of zinc and nickel. At the same time in patients with moderate to marked decrease of the passage not only of zinc and calcium. It was found that with increasing severity of hives and the concentration of nickel chloride is reduced. The level of zinc and copper were significantly more elevated in children with underlying allergic diseases. Dismikroelementoz revealed features in children with different degrees of severity of urticaria determine their corrections in the process of treatment of the disease.