World Science

THE STRATEGIES FOR ENHANCING TRANSPORTATION MANAGEMENT AT THE BORDER PORTS BETWEEN MONGOLIA AND CHINA

Munkhzaya Bayanmunkh — 2024-11-15

Effective management of border port road transport is crucial for enhancing trade and economic potential at border ports and free zones. This involves long-term, medium-term, and short-term planning, as well as the implementation of integrated development policies to ensure sustainable and accessible improvements. By connecting border ports with railways and paved roads, enhancing transport and logistics competitiveness, optimizing cargo flow, and laying the groundwork for future transit capabilities, economic relations and cooperation between Mongolia and China can flourish, fostering the sustainable development of both nations. To boost trade turnover and establish free economic zones and road ports, it is imperative to enhance the management of border port road transport in alignment with Mongolia's regional development strategy. Currently, the concentration of the economy on only four ports leads to goods shortages, price hikes, and hindered business operations. Therefore, enhancing the type, quality, and availability of road transport services at border ports is essential to increase the throughput capacity of these crucial transportation hubs.

STUDIES OF ASTHMA CONTROL IN PATIENTS WITH METABOLIC SYNDROME

Daria Lahoda — 2024-11-15

Every day, a practitioner is faced with the problem of patient comorbidity. Bronchial asthma is a common problem, as is metabolic syndrome. Due to the increase in allergic diseases and lifestyle changes, patients may have a combination of metabolic syndrome and bronchial asthma. This combination has been shown to aggravate the course of asthma. Therefore, we wanted to confirm or refute this with our study. The study design included 94 patients with a diagnosis of asthma. A comparative analysis of the spirographic study data revealed that patients with asthma + MetS had statistically significant differences (p<0.05). The analysis of anthropometric data revealed that patients with the highest BMI and body weight had a significantly more severe course of asthma (p<0,05), which is consistent with the data of available world studies [24, 25], and a positive correlation was found between BMI, percentage of body fat and lower percentage of body fat in patients with severe asthma (ρ=0,89, ρ=0,90, ρ=0,87; r=0,88, r=0,91, r=0,90, respectively). The data obtained indicate the need for individual management of patients with comorbidities, including MetS and asthma, to prevent severe asthma, which is associated with inadequate asthma control and poor quality of life.

CHOICE IN FAVOR OF TRIMETAZIDINE. ANALYSIS OF A CLINICAL CASE

K.V. Vovk — 2024-12-29

Cardiovascular diseases (CVD) are the leading cause of death and disability among adults in the world. The key position in the structure of causes of death from CVD is occupied by coronary heart disease (CHD), the most common form of which is stable angina. The goals of treatment for patients with chronic angina should be to relieve symptoms and reduce mortality. This will allow patients to feel better and live longer. The traditional hemodynamic approach to the treatment of CAD is based on the belief that increasing oxygen supply and decreasing cardiomyocyte oxygen demand improves symptoms. However, clinical trial data demonstrate that about a third of patients, despite antianginal therapy, continue to experience anginal pain. Traditional tactics for managing patients with stable angina usually involve the use of drugs that affect circulatory parameters (heart rate, blood pressure). The article presents a clinical case demonstrating the effectiveness of trimetazidine monotherapy in stable coronary artery disease, when the use of first-line drugs (beta blockers, calcium antagonists and nitrates) is not possible. Trimetazidine modulates cardiac metabolism without changing hemodynamic functions, so its use in this clinical situation is optimal. Modulators of cardiac metabolism open the way to a deeper understanding of CAD and its general clinical manifestations as an energy disorder, not just an imbalance between the demand and supply of oxygen and metabolites