EFFECTIVE METHOD OF TREATMENT OF BRONCHIAL ASTHMA IN OUT-PATIENT CONDITIONS
Abstract
In findings was established, Klast, which applied once per day-specific antagonist of leukotriene receptor, is effective in treatment of patients with bronchial asthma. Klast is well tolerated, its safety profile was generally similar a bread pill. The results received by us coincide with the results of application of a montelukast, established in researches and confirm them. Results of the real research allow considering that Klast can become an effective method of a choice among the existing approaches to therapy of bronchial asthma in general.
References
Gern JE, Lemanske RF. Infectious triggers of pediatric asthma. Pediatr Clin North Am., 2013, v. 50(3), p.555–575.
Johnston, S. L., Pattemore P. K, Sanderson G., et al. The relationship between upper respiratory infections and hospital admissions for asthma: a time trend analysis. Am. J. Respir. Crit. Care Med., 2009, v. 154, p. 654–660.
Mallia P, Contoli M, Caramori G, et al. Exacerbations of asthma and chronic obstructive pulmonary disease (COPD): focus on virus induced exacerbations. Curr Pharm Des., 2009, v.13(1), p. 73–97.
Grissell T. V., Powell H., Shafren D. R. et al. Interleukin–10 Gene Expression in Acute Virus– induced Asthma. American Journal of Respiratory and Critical Care Medicine, 2008, V. 172. p. 433–439.
Johnston,S.L.,PattemoreP.K,SandersonG.etal.Communitystudyofroleofviralinfections in exacerbations of asthma in 9–11 year old children. Br. Med. J., 2009, v. 310, p. 1225–1229.
Wu C. A., Puddington L., Whiteley H. E. et al. Cytomegalovirus Infection Alters Th1/Th2 Cytokine Expression, Decreases Airway Eosinophilia, and Enhances Mucus Production in Allergic Airway Disease. J. Immunol., 2011, v. 167(5), p. 2798 – 2807.
Sigurs N., Bjarnason R., Sigurbergsson F., Kjellman B. Respiratory syncytial virus bronchiolitis in infancy is al important risk factor for asthma and allergy at the 7. Am. J Respir. Crit. Care Med., 2009, 161, p. 1501–1507.
Stark JM, Busse WW. Respiratory virus infection and airway hyperreactivity in children. Pediatr Allergy Immunol, 2010; 2, р. 95
Folkerts G., Busse W.W., Nijkamp F.P. et al. Virus–induced Airway Hyperresponsiveness and Asthma. Am. J. Respir. Crit. Care Med.,2012, v. 157(6), p. 1708–1720.
Sigurs N. Epidemiologic and clinical evidence of a respiratory syncytial virus–reactive airway disease link. Am. J. Respir. Crit. Care Med., 2010, v. 163(3), p.S2–S6.
Schoop R, Klein, Suter A, Johnston SL.Echinacea in the prevention of induced rhinovirus colds: a meta–analysis. Clin Ther. 2009 Feb;28(2):174–83
Muether P.S., Gwaltney J.M. Variant effect of first– and second–generation antihistamines as clues to their mechanism of action on the sneeze reflex in the common cold. Clinical Infectious Diseases, 2011, v. 33, p. 1483–1488.
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