SYNTHESIS OF SOME NOVEL BENZIMIDAZOL-2-ONE DERIVATIVES
Abstract
For the development of medical and pharmaceutical chemistry is essential to optimize and change relevant structures, possessing biological activity. Herein we report the synthesis of some novel 1H-benzimidazolon-2-one derivatives using aza-Michael addition.
References
Anna-Maria Monforte , P. Logoteta, L. De Luca , N. Iraci , S. Ferro et al.; Bioor & Med Chem, 2010, 18, 1702–1710.
G. Remond, B.Portevin, J.Bonnet, E.Cnaet, Regoli D, Denanteuil G, Eur J Med Chem, 1997, 32, 843-868.
D.Zuev, J.A. Michne, H. Huang, B.R. Beno, D. Wu, Q. Gao, et al., Org Lett, 2005, 7, 2465–2468.
Q.T.Li,K.W.Woods,W.Z.GuJ.Cohen,etal.BioorgMedChemLett,2005,15,2918–2922.
F.J.Sweeney,C.H.Yu,BioorgMedChemLett,2004,14,919–923.
M.N.Mansour,E.S.Marr,M.A.Letavic,J.Pandit,D.B.Ripin,F.J.Sweeney,D.Tan,Y.TaoY,J Med Chem, 2005, 48, 5728–5737.
D.J.Gustin, C.A. Sehon, J. Wei, H.Cai, S.P. Meduna et a.l;. Bioorg Med Chem Lett, 2005, 15, 1687–1691.
K-L.Yu,Y.Zhang,R.L.Civiello,A.K.Trehan,B.C.Pearceetal.,BioorgMedChemLett,2004, 14,1133–1137.
B. D. Mather , K. Viswanathan , K.M. Miller , T. E. Long, Prog. Polym. Sci., 2006, 31, 487– 531.
Lee, V. J. In Comprehensive Organic Synthesis; B. M. Trost, I. Fleming (Eds.); Pergamon Press: New York, 1991, vol. 4, chap. 1.2.69;
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