POSSIBLE ROLE OF NITRIC OXIDE IN REGULATION OF MICROCIRCULATION IN THE ORAL CAVITY TISSUES OF RAT

Dekanosidze M.; Saganelidze Kh.; Mamaladze M.; Sakvarelidze N.; Diasamidze G.; Mitagvaria N.

doi:10.31435/rsglobal_ws/28022019/6353

Dekanosidze M. New Vision University, Georgia
Saganelidze Kh. New Vision University, Georgia
Mamaladze M. Tbilisi State Medical University, Georgia
Sakvarelidze N. Tbilisi State Medical University, Georgia
Diasamidze G. Association of Dentists of Georgia, Georgia
Mitagvaria N. Beritashvili Center for Experimental Biomedicine, Georgia

DOI: https://doi.org/10.31435/rsglobal_ws/28022019/6353

Keywords: Nitric Oxide, L-NAME, local blood flow, oral tissue, rat

Abstract

Possible role of Nitric oxide (NO) in terms formation of basal blood flow level in oral cavity tissue is studied using the method of hydrogen electrochemical generation in anesthetized rats.
It was found that NO plays a leading role in oral mucosa and submandibular gland basal blood flow regulation and does not have any significant effect on blood circulation of the lower snout tissue.

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