FEATURES OF THE CLINIC AND DIAGNOSIS OF CROHN'S DISEASE IN CHILDREN AT THE PRESENT STAGE

Denisova M. F.; Chernega N.V.; Muzika N.N.; Bukulova N.Y.; Archakova T.N.; Reminnaia N.T.; Doroshenko O.A.

doi:10.31435/rsglobal_ws/28022022/7779

Denisova M. F. professor, candidate of Medical Sciences, Institute of Pediatrics, Obstetrics and Gynecology of the National Academy of Medical Sciences of Ukraine, Ukraine
Chernega N.V. candidate of Medical Sciences, Institute of Pediatrics, Obstetrics and Gynecology of the National Academy of Medical Sciences of Ukraine, Ukraine
Muzika N.N. candidate of Medical Sciences, Institute of Pediatrics, Obstetrics and Gynecology of the National Academy of Medical Sciences of Ukraine, Ukraine
Bukulova N.Y. candidate of Medical Sciences, Institute of Pediatrics, Obstetrics and Gynecology of the National Academy of Medical Sciences of Ukraine, Ukraine
Archakova T.N. candidate of Medical Sciences, Institute of Pediatrics, Obstetrics and Gynecology of the National Academy of Medical Sciences of Ukraine, Ukraine
Reminnaia N.T. doctor Institute of Pediatrics, Obstetrics and Gynecology of the National Academy of Medical Sciences of Ukraine, Ukraine
Doroshenko O.A. Institute of Pediatrics, Obstetrics and Gynecology of the National Academy of Medical Sciences of Ukraine, Ukraine

DOI: https://doi.org/10.31435/rsglobal_ws/28022022/7779

Keywords: Crohn's disease, children, clinic, diagnostics.

Abstract

Based on a retrospective analysis of case histories, the article presents modern data on the features of the clinical course of Crohn's disease in childhood, laboratory, endoscopic and morphological markers of the disease. The symptomatology of Crohn's disease is described in the onset and in the period of the developed clinical picture, depending on the localization of the inflammatory process.

References

Magro F, et al. Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extraintestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders. J Crohns Colitis. 2017; 11 (6): 649-670.

Roberts SE, et al. A Systematic Review and Meta–analysis of Paediatric Inflammatory Bowel Disease Incidence and Prevalence Across Europe. J Crohns Colitis. 2020 Sep 7;14(8):1119–1148. doi: 10.1093/ecco–jcc/jjaa037.

Benchimol EI, et al. Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada: Distributed Network Analysis of Multiple Population– Based Provincial Health Administrative Databases. The American Journal of Gastroenterology. 2017; (112): 1120–1134. doi:10.1038/ajg.2017.97

Степанов В.Г. и др. Хронические воспалительные заболевания кишечника: особенности эпидемиологии в Украине. Гастроентерология.2017;51(2):97-105.

Тагирова А.Р., Сичинава И.В., Савватеева О.А., Борисова Е.В. Качество жизни детей с болезнью Крона как потенциальный критерий мониторинга активности заболевания. Доктор.ру.2020; 19(10):27-32. DOI:10.31550/1727-2378-2020-19-10-27-32).

Putowski M, et al. Inflammatory bowel disease in children. Journal of Education, Health and Sport. 2019;9(8):406–411. DOI http://dx.doi.org/10.5281/zenodo.3379040

Крючкова Т.В. и соавт. 2017, Фармация №12(261) вып.38 с.180-1861.

Мазанкова Л.Н., Халиф И.Л., Водилова О.В. «Болезнь Крона у детей: принципы диагностики и лечения» (2008 г.)

Терещенко С.Ю., Прахин Е.И. и др. «Болезнь Крона у детей и подростков: диагностика и современные подходы к терапии» журнал- Современная педиатрическая фармакология 2009г.

Бекетова Г.В., Солдатова О.В. «Болезнь Крона у детей и подростков» (клинические лекции) 2017г.

Румянцева Г.Н. и др. Болезнь Крона у детей. Верхневолжский медицинский журнал. 2016; 15(1): 24-30. eLIBRARY ID: 255898002.

Guideline Update. J Crohns Colitis 2021; 15(2):171-194.

Ruemmele FM, El Khoury MG, Talbotec C, Maurage C, Mougenot JF, Schmitz J, Goulet O. Characteristics of inflammatory bowel disease with onset during the first year of life. J Pediatr Gastroenterol Nutr. 2006; 43(5):603–9.