THE ROLE OF THE FUNCTIONAL CONDITION OF ERYTHROCYTES IN DETERMINING THE PROGNOSIS IN PATIENTS WITH BURN INJURY

Fadieiev Pavlo; Alona Gryshchenko

doi:10.31435/rsglobal_ws/28022021/7439

Fadieiev Pavlo Postgraduate student, Kharkiv national medical university, Kharkiv, Ukraine https://orcid.org/0000-0003-0413-0809
Alona Gryshchenko Postgraduate student, Kharkiv National University named after N. V. Karazin, Kharkiv, Ukraine https://orcid.org/0000-0003-4847-3088

DOI: https://doi.org/10.31435/rsglobal_ws/28022021/7439

Keywords: burn injury, hemolysis, oxidative stress, ceruloplasmin, D-fructose-1,6-diphosphate sodium salt hydrate

Abstract

In the event of a burn injury, one of the leading pathogenetic mechanisms of complications is intravascular hemolysis of erythrocytes. Oxidative stress is the initiating factor in the development of hemolysis. The appointment of ceruloplasmin solution is pathogenetically directed at clinical signs of burn shock. Its appointment during a 10-day stay in the clinic is an important component of the intensive care unit. Determining the indices of the functional state and architecture of erythrocytes is an important component of the diagnostic program for burn trauma.

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