• Brubaker I. O. Ph.D. in Pharmaceutical Science, Assistant Professor, Department of Pharmaceutical Management, Clinical Pharmacy, Drug Technology, PHEE "Kyiv Medical University", Kyiv, Ukraine
  • Bilan O. A. Senior Lecturer, Department of Pharmaceutical Management, Clinical Pharmacy, Drug Technology, PHEE "Kyiv Medical University", Kyiv, Ukraine
  • Marchenko-Tolsta K. S. Assistant, Department of Pharmacology, Clinical Pharmacology, Pathophysiology, PHEE "Kyiv Medical University", Kyiv, Ukraine
Keywords: nanomedicine, nanopharmacy, nanobiosensors, theranostics, nanotoxicology, nanorobots


The review examines current trends in the development of biomedical nanotechnology, its application in various fields of medicine and prospects for further development. Among the main directions — monitoring and control of delivery, distribution and use of drugs; nanobiosensors; diagnostics of pathological states; theranostics; use of nanostructured materials in regenerative medicine; nanotoxicology; nanophytopharmacy; green synthesis; development of new nanobiotech devices and nanorobototics.


Anil M, Singh DK. Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines. J Nanobiotechnology 2011; 9: 55.

Brubaker I. O., Bilan O. A., Marchenko-Tolsta K. S. (2020) Review of Modern Approaches to the Development of Nanodrugs. World Science. 5(57), 55-59. Vol.2. doi: 10.31435/rsglobal_ws/31052020/7081.

Brubaker, I., Bilan, O., & Marchenko-Tolsta, K. (2020). Modern approaches to development of nano-systems for drug delivery. World Science. 1(6(58), 32-37. doi: 10.31435/rsglobal_ws/30062020/7102.

Critchley L. The Rise of Nanomedicine. Nano magazine 2018, Issue 04.

Deepa V, Sridhar R, Goparaju A, Reddy PN, Murthy PB. Nanoemulsified ethanolic extract of Pyllanthus amarus Schum & Thonn ameliorates CCl4 induced hepatotoxicity in Wistar rats. Indian J Exp Biol. 2012;50(11):785-794.

Diab R, Jaafar-Maalej C, Fessi H, Maincent P. Engineered nanoparticulate drug delivery systems: the next frontier for oral administration? AAPS J 2012; 14: 688-702.

Grewal DS. Funding Nanotechnology-A Comparative Study of Global and National Funding. Journal of Nanomedicine, Nanoscience and Technology Vol. 2019, Issue 01, pp. 1-10.

Gunasekaran T, Hailea T, Nigussea T, Dhanarajub MD. Nanotechnology: an effective tool for enhancing bioavailability and bioactivity of phytomedicine. Asian Pacific Journal of Tropical Biomedicine 2014, Vol. 4(1), pp. S1-S7. doi:10.12980/APJTB.4.2014C980

Kad D, Hodgar S, Thorat K. Nanorobotics: medicine of the future. World journal of pharmacy and pharmaceutical sciences 2018, Vol. 7(8), pp.1393-1416.

Kalani M, Yunus R. Application of supercritical antisolvent method in drug encapsulation: a review. Int J Nanomedicine 2011; 6: 1429-1442.

Mora L, Chumbimuni-Torres KY, Clawson C, Hernandez L, Zhang L, Wang J. Real-time electrochemical monitoring of drug release from therapeutic nanoparticles. Journal of Control Release 2009, Nov 16;140(1):69-73. doi: 10.1016/j.jconrel.2009.08.002.

Nandedkar TD. Nanovaccines: Recent Developments in Vaccination. Journal of Biosciences 2009 Dec;34(6):995-1003. doi: 10.1007/s12038-009-0114-3.

Nanomedicine Market - Global Opportunity Analysis and Industry Forecast, 2017-2023. 2017, 190 p. Report ID: 5139404.

Pallavi K, SRITEJA T. Pharmacyte — magical nano-bullet for drug targeting. The Indian Pharmacist Vol. XIII(09), 2016, March, pp. 15-20.

Rane J, Patil U, Patil N, Pawar P, Patil VR. Nanobaots: an overview. World Journal of Pharmaceutical and Life Sciences 2019, Vol. 5, Issue 6, pp. 118-132.

Rohit S, Hazra J, Prajapati P. Nanophytomedicines: A Novel Approach to Improve Drug Delivery and Pharmacokinetics of Herbal Medicine. Bio Bulletin 2017, Vol. 3, pp. 132-135.

Rösslein M, Liptrott NJ, Owen A, Boisseau P, Wick P, Herrmann IK. Sound understanding of environmental, health and safety, clinical, and market aspects is imperative to clinical translation of nanomedicines. Nanotoxicology 2017, 11, pp. 147-49.

Sachan AK, Gupta A. A review on nanotized herbal drugs. International journal of pharmaceutical sciences and research 2015, Vol 3.

Sahni JK, Baboota S, Ali J. Promising role of nanopharmaceuticals in drug delivery. Pharma Times 2011; 43: 16-18.

Sandhiya S, Adithan S, Dkhar SA. Emerging trends of nanomedicine – an overview. Fundamental and Clinical Pharmacology 2009, July. DOI: 10.1111/j.1472-8206.2009.00692.x.

Singh P, Kim Y-J, Zhang D, Yang D-C. Biological synthesis of nanoparticles from plants and microorganisms. Trends in biotechnology 2016 Jul;34(7):588-599. doi: 10.1016/j.tibtech.2016.02.006.

How to Cite
Brubaker I. O., Bilan O. A., & Marchenko-Tolsta K. S. (2020). INNOVATIONS IN NANOMEDICINE AND NANOPHARMACY. World Science, (7(59).