МОДИФИЦИРОВАНИЕ КОЛЛАГЕНА И ЖЕЛАТИНА ПОД ДЕЙСТВИЕМ МИКРОВОЛНОВОГО ПОЛЯ
Abstract
The microwave field influence on the physicochemical properties of collagen and gelatin was studied. It is shown that when microwave field acts on the studied protein samples, a change in the molecules structure formation occurs. It was experimentally established that microwave exposure leads to the structural modification of collagen and gelatin molecules. This modification is accompanied by a change in the physicochemical properties of the studied biopolymers. It is shown that microwave field exposure leads to a decrease in the viscosity of collagen and gelatin solutions. A decrease in viscosity indicates that there’s a structural or transient processes occurring in protein molecules.
The kinetics of swelling with time for collagen and gelatin samples was studied. It is shown that the use of a microwave field leads to a decrease in the rate constant of swelling. The swelling degree of the studied samples decreases on average by 60%. It is shown that isoelectric points of the proteins are shifted (pI from 5 to 6 for collagen and up to 5.5 for gelatin).
References
Вейс, А. Макромолекулярная химия желатина – М.: Пищ. пром-сть, 1971.478.
Зіменковський Б.С., Музиченко В.А. Біоорганічна хімія. – Львів: Кварт. 2009. 402.
Михайлов, А. Н. Химия и физика коллагена кожного покрова: монография – М.: Легкая индустрия, 1980. 232.
Неклюдов, А.Д., А.Н. Иванкин А.Н. Коллаген: получение, свойства и применение: монография. – М.: ГОУ ВПО МГУЛ, 2007. 336.
Джафаров, А.Ф. Производство желатина. – М.: Агропромиздат, 1990. 287.
Семенов, Г.В. Основы теории, техники и технологи сублимационной сушки – М.: МГАПБ, 2003. 89.
Саевич О.В., Чернушенко О.О. Вплив мікрохвильової сушки на структуру желатину. Праці Таврійського державного агротехнологічного університету, 2018, Вип.18, Т1.,167-173.
Ганзюк Л.І. Основи хімії і фізики високомолекулярних сполук. Т.1. Загальні положення. Волокноутворюючі полімери. Сучасні методи досліджень полімерів: Навч. посібник. – Хмельницький: ТУП, 2002. 235.
Драббе А. Практическая химия белка. – М.: Мир, 1989. 623.
Завлин П.М., Измайлова В.Н., Сакварелидзе М.А., Ямпольская Г.П. Структура и свойства коллагена - источника и предшественника желатины. Журнал прикладной химии (ЖПХ), 1993. Т.66, No2. 320-335.
Vandelli, M.-A., M. Romagnoli, A. Monti, M. Gozzi, P. Guerra, F. Rivasi, and F. Forni, Microwave-treated gelatin microspheres as drug delivery system, J. Controlled Release, 2004, Vol. 96, 67–84.
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