LABOR COURSE AND CONDITION OF NEWBORNS IN WOMEN WITH PLACENTAL DYSFUNCTION DUE TO GESTATIONAL ENDOTHELIOPATHY

  • V. V. Lazurenko Prof., MD, Head of t Department of Obstetrics and Gynecology No. 2, Ukraine, Kharkiv, Kharkiv National Medical University
  • I. B. Borzenko Post-graduate student, Post-graduate student of the Department of Obstetrics and Gynecology No.2, Ukraine, Kharkiv, Kharkiv National Medical University
  • D. Yu. Tertyshnik Post-graduate student, Post-graduate student of the Department of Obstetrics and Gynecology No.2, Ukraine, Kharkiv, Kharkiv National Medical University
Keywords: gestational endotheliopathy, placental dysfunction

Abstract

The purpose of the study is to evaluate the effect of placental dysfunction caused by gestational endotheliopathy on the course of labor and the condition of the newborn. The first group consisted of 70 patients with placental dysfunction with gestational endotheliopathy confirmed by laboratory-instrumental findings in the first trimester of pregnancy. The control group included 30 pregnant women with physiological gestational course. PD secondary to GE leads to preterm birth, fetal distress, increases the percentage of caesarean section, contributes to the delay of fetal growth and birth weight, poor infant status and perinatal complications.

References

Игнатко, И.В. Прогностические маркеры синдрома задержки роста плода / И.В. Игнатко, М.М. Мирющенко // Журнал научных статей «Здоровье и образование в XXI веке». - 2016. - Т.18, No 1. - С.1-4.

Коньков Д.Г. Патогенез та профілактика перинатальних втрат що обумовлені ендотеліальною дисфункцією: дис. ... доктора мед. наук: 14.01.01 / Д.Г. Коньков – Вінниця, 2015. – 361 с.

Овчарук В.В. Клініко-патогенетичні аспекти діагностики та профілактики плацентарної дисфункції: дис. ... канд. мед. наук: 14.01.01 / В.В. Овчарук - Тернопіль, 2017. - 213 с.

Amato, N.A. Placental insufficiency and intrauterine growth retardation / N.A. Amato, G. Maruotti, G. Scillitani et al. // Minerva Ginecol. 2007. - Vol. 59, N 4.-P 357-367.

Burton, G.J., Fowden, A.L., Thornburg, K.L. Placental origins of chronic disease. Physiol Rev. 2016;96:1509–1565.

Crocker I.P. Review: Endothelial progenitor cells in pregnancy and obstetric pathologies / I P. Crocker, P.I. Sipos // Placenta. – 2013. – Vol. 34, suppl. – P. S62-S67.

McCowan L.M., Figueras F., Anderson N.H. Evidence-based national guidelines for the management of suspected fetal growth restriction: comparison, consensus, and controversy. Am J Obstet Gynecol. 2018; 218(2S):S855-S868.

Rabinovich A, Tsemach T, Novack L, et al. Late preterm and early term: when to induce a growth restricted fetus? A population-based study. J Matern Fetal Neonatal Med 2017 Mar 22:1e7.

Veerbeek, J.H., Nikkels, P.G., Torrance, H.L. et al, Placental pathology in early intrauterine growth restriction associated with maternal hypertension. Placenta. 2014; 35:696–701.

Zhang, S., Regnault, T., Barker, P., Botting, K., McMillen, I., McMillan, C., et al. Placental adaptations in growth restriction. Nutrients. 2015. 7, 360–389.

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Published
2019-09-30
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How to Cite
V. V. Lazurenko, I. B. Borzenko, & D. Yu. Tertyshnik. (2019). LABOR COURSE AND CONDITION OF NEWBORNS IN WOMEN WITH PLACENTAL DYSFUNCTION DUE TO GESTATIONAL ENDOTHELIOPATHY. World Science, 2(9(49), 4-8. https://doi.org/10.31435/rsglobal_ws/30092019/6704