ЕЛЕКТРОННОМІКРОСКОПІЧНІ ДОСЛІДЖЕННЯ ПАРОДОНТА ПРИ ДІЇ ОПІОЇДУ ВПРОДОВЖ ШЕСТИ ТИЖНІВ
Abstract
The following work is aimed at studying the features of the restructuring of the structural components of periodontal tissues under the conditions of a six-week experimental effect of an opioid analgesic at the ultrastructural level. Destructive changes were found in all cellular components of the mucous membrane of the gums, the periodontium and in the links of the microcirculatory bed. The ultrastructural manifestations in periodontal tissues that occur with the action of an opioid analgesic for six weeks may serve as a morphological basis for further study of the dynamics of submicroscopic changes in the later stages of opioid exposure in the experiment.
References
Brauchle F., Noack, M., & Reich, E. (2013). Impact of periodontal disease and periodontal therapy on oral health-related quality of life. Int. Dental J., 63, 306–311. PMID: 24716244
Rosier BT, de Jager M, Zaura E, Krom BP. (2014) Historical and contemporary hypotheses on the development of oral diseases: are we there yet? Front Cell Infect. Microbiol. 4:92 doi: 10.3389/fcimb.2014.00092.
Слинько Ю.А. Морфофункциональные особенности строения эпителия десны крыс при разном двигательном режиме их матерей в период вынашивания / Ю.Я. Слинько, Г.И. Губина-Вакулик, Е.Н. Рябоконь, И.И. Соколова // Український стоматологічний альманах. 2013. No 6 С. 6 – 9
Бакулин И.И. Ультраструктурный анализ слизистой оболочки десны при хроническом гингивите / И.И.Бакулин: Автореф. дис. на соиск. науч. степ. канд.мед.наук. Спец. 14.03.02 “Патологическая анатомия”. 2010. 95 с.
Подгаецкая О.Е. Этиология и патогенез хронического генерализованного пародонтита (обзор литературы) / О.Е. Подгаецкая, С.А. Шнайдер // Буковинський медичний вісник. 2007. 11 (1). С. 127-130.
Зубачик В.М. Стан органів порожнини рота в осіб, які зловживають наркотичними речовинами. Огляд літератури / В.М.Зубачик, І.Р.Федун // Новини стоматології. 2015. No3. С. 71-74.
Фік В.Б. Морфологія тканин пародонта щурів при шеститижневій дії опіоїду / В.Б.Фік // Світ медицини та біології. 2018. 4 (66). С. 218-222. DOI 10.26724/2079-8334-2018-4-66-222-226
Fik VB, Paltov EV, Lohash MV, Kryvko YuYa (2017) Pecularities of morphological manifestation of the periodontal tissue in experimental animals against the ground of a short-term effect of opioid analgesic. Deutsch. Wissenscaftsch. Jul 25; 2: 54-8. DOI:10.19221/2017215
Berna C, Kulich RJ, Rathmell JP. (2015) Tapering long-term opioid therapy in chronic noncancer pain: Evidence and recommendations for everyday practice. Mayo Clin Proc. 90:828–42. doi: 10.1016/j.mayocp.2015.04.003.
Dowell D, Haegerich TM, Chou R. (2016) CDC guideline for prescribing opioids for chronic pain—United States. MMWR Recomm Rep. 65(1). DOI: 10.1001/jama.2016.1464
Jamison RN, Sheehan KA, Scanlan E, Matthews M, Ross EL. (2014) Beliefs and attitudes about opioid prescribing and chronic pain management: survey of primary care providers. J Opioid Manag. 10:375–82. doi: 10.5055/jom.2014.0234.
Garg RK, Fulton-Kehoe D, Franklin GM (2017). Patterns of opioid use and risk of opioid overdose death among Medicaid patients. Med Care 55: 661–68. doi: 10.1097/MLR.0000000000000738.
Garg RK, Fulton-Kehoe D, Franklin GM (2017). Patterns of opioid use and risk of opioid overdose death among Medicaid patients. Med Care 55: 661–668. doi: 10.1097/MLR.0000000000000738.
Paltov, YV, Fik, VB, Vilchova, IV, Onisco, RM, Fitkalo, OS., Kryvko Y.Ya (2013) Ukraine. Patent No. 76565. Kyiv: Ukrainian Institute of Intellectual Property (Ukrpatent).
Views:
320
Downloads:
166
Copyright (c) 2019 The authors
This work is licensed under a Creative Commons Attribution 4.0 International License.
All articles are published in open-access and licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). Hence, authors retain copyright to the content of the articles.
CC BY 4.0 License allows content to be copied, adapted, displayed, distributed, re-published or otherwise re-used for any purpose including for adaptation and commercial use provided the content is attributed.
