DIAGNOSTIC VALUE OF SYSTEMIC LUPUS ERYTHEMATOSUS CLASSIFICATION CRITERIA (AMERICAN COLLEGE OF RHEUMATOLOGY, 1997)

U. Abrahamovych; O. Abrahamovych; O. Nadashkevych; A. Svintsitskyi; O. Synenkyi

doi:10.31435/rsglobal_wos/30042020/7041

U. Abrahamovych Danylo Halytsky Lviv National Medical University
O. Abrahamovych Danylo Halytsky Lviv National Medical University
O. Nadashkevych Danylo Halytsky Lviv National Medical University
A. Svintsitskyi Bogomolets National Medical University
O. Synenkyi Communal Non-profit Institution of Lviv Regional Council "Lviv Regional Clinical Hospital"

DOI: https://doi.org/10.31435/rsglobal_wos/30042020/7041

Keywords: systemic lupus erythematosus, American College of Rheumatology criteria, diagnosis, sensitivity, specificity, accuracy

Abstract

The criteria for the classification of systemic lupus erythematosus were proposed in 1971 by the American College of Rheumatology. They have been clarified since then, but need to be revised.
Objective. To determine the diagnostic value of the criteria for the classification of systemic lupus erythematosus proposed by the American College of Rheumatology.
Materials and methods. 370 patients (331 women (89.46%) and 39 men (10.54%), average age 41.24 ± 0.63 years) with SLE and 234 patients (150 women (64.10%) and 84 men (35.90%), average age 48.82 ± 0.85 years) with other rheumatic diseases (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis) were randomly enrolled into the study. The patients had undergone comprehensive clinical-laboratory and instrumental examinations in 2010–2018 before they received treatment. The analysis was conducted in MS Excel and SPSS by constructing contingency tables and calculating indicators of diagnostic value.
Results. We identified the following criteria as those that can with statistical significance predict the presence of systemic lupus erythematosus: butterfly rash, photosensitivity, serositis (pleuritis, pericarditis), neurologic disorders (seizures, psychosis), thrombocytopenia, renal disorders (proteinuria, cylindruria), anti-dsDNA and antinuclear antibodies.

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