ДИНАМІКА МОРФОЛОГІЧНИХ ЗМІН СТРУКТУРНИХ КОМПОНЕНТІВ ХРЯЩОВОГО ПОКРИТТЯ КОЛІННОГО СУГЛОБА НА УЛЬТРАСТРУКТУРНОМУ РІВНІ НА СУБХРОНІЧНОМУ ТА ХРОНІЧНОМУ ПЕРІОДАХ ЕКСПЕРИМЕНТАЛЬНОГО ОПІОЇДНОГО ВПЛИВУ НАПРИКІНЦІ ЧЕТВЕРТОГО, П’ЯТОГО ТА ШОСТОГО ТИЖНІВ
Abstract
The work, presented below, aimed at studying the dynamics of structural disorganization of morphological components of the articular cartilage at ultrastructural level in subchronic and chronic periods of experimental opioid chondrodystrophy. The purpose was achieved by ultrastructural visualization of the components of the articular cartilage. Generally accepted conventional methods were used for obtaining microstructural material.
The results of the study will form pathomorphological basis, which can be applied for the development of diagnostic criteria for lesions of the articular cartilage at different stages of opioid exposure. Furthermore, pathomorphological findings will form the basis for effective medical handling of opioid chondrodystrophy of the articular cartilage and its consequences.
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